Chemistry
Why does a crystallisation proceed abnormally at certain temperature cycles?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
EXPLANATORY RESEARCH · TSR
Technical scientific research (technisch-wetenschappelijk onderzoek, TWO) is explanatory research into a technical phenomenon for which, based on publicly accessible and internally available knowledge, no adequate explanation yet exists. The research must be carried out systematically and according to a plan, and must yield new theoretical or practical technical knowledge. A practical application purpose does not preclude TWO; decisive is that the research is aimed at explaining the phenomenon.
BY PETER KLAREN · UPDATED 19 SEPTEMBER 2026 · SOURCE: RVO WBSO GUIDE 2026
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In the official project form, RVO successively asks about the phenomenon, existing knowledge, research questions, research design, intended new knowledge and technology field. Translated into five questions:
If you can answer these questions convincingly, TWO may apply. The final answer does not have to be known in advance; there must in fact be a real risk that the explanation will not be found.
This is the most important delineation in research. The research must explain, not merely observe, describe, monitor, inventory, code, classify or translate. Merely finding correlations is also not sufficient.
| Research | Research? | Why |
|---|---|---|
| Determining at which temperature a material deforms | Usually not | Descriptive/measuring, no explanation. |
| Investigating which mechanism causes the deformation at that temperature | Possibly yes | Explanatory research into the underlying mechanism. |
| Testing various process settings and choosing the best setting | Usually not | Optimising/descriptive, no explanation sought. |
| Investigating why an unexpected material reaction occurs | Possibly yes | Explanation of the operating mechanism. |
| Analysing historical data to predict failures | Not in itself | Predictive/correlative, not explanatory. |
| Investigating the mechanism behind unexpected corrosion | Possibly yes | Explanatory technical research. |
| Comparing various preservation methods | Usually not | Establishing an effect, no explanation. |
| Investigating cellular mechanisms behind different behaviour | Possibly yes | Explanation of an underlying mechanism sought. |
RVO accepts research within technical technology fields such as physics, chemistry, biotechnology, production technology and information and communication technology. Economic, social and psychological research does not fall under it, even if carried out systematically.
| Research field | Technical in principle? |
|---|---|
| Materials physics | Yes |
| Chemical reactions | Yes |
| Biotechnology | Yes |
| Production technology | Yes |
| ICT / information technology | Yes |
| Corrosion mechanisms | Yes |
| Consumer behaviour | No |
| Economic models | No |
| Organisational research | No |
| Psychological research | No |
No. For WBSO you do not have to discover a new law of nature or scientific theory. The research must yield theoretical or practical technical knowledge that is new for your company, because the explanation for the researched phenomenon cannot be obtained from publicly accessible or internally available knowledge.
RVO also does not require the outcome to be proven reproducible or statistically significant as in academic research.
RVO formally distinguishes two project types: development projects and technical scientific research.
| Aspect | Technical scientific research | Development project |
|---|---|---|
| Question | Why does this happen? | How do we solve this technically? |
| Goal | Obtaining an explanation | Realising a technically new operating principle |
| Result | New knowledge | Prototype, model, principle or software |
| Risk | The explanation may not be found | The technical solution may not work |
| End of project | The research question has been answered | The operating principle has been demonstrated |
Within one broader innovation programme, both types of activities can occur; the WBSO application must then delineate them correctly in substance. Are you mainly developing a technical solution? Then see WBSO product development or WBSO process development.
Our own practical example: research into crystallisation behaviour in a coating process for which no existing model describes the course. See this case elaborated at compiled WBSO cases.
Why does a crystallisation proceed abnormally at certain temperature cycles?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
Which mechanism causes unexpectedly fast corrosion?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
Why does the activity of a protein change under certain conditions?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
Which mechanism causes delamination after cyclic loading?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
Why does unexpected instability occur during scale-up?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
Why does a complex technical information system exhibit certain unexplained behaviour?
PHENOMENON → KNOWLEDGE INSUFFICIENT → RESEARCH QUESTION → METHOD → NEW INSIGHT
They are anonymised example situations, not claims about specific clients.
Doubting whether your research is sufficiently explanatory? Test it against the five RVO assessment questions above.
AI can be a research tool within technical scientific research, but the use of AI is not decisive. The question remains whether you are trying to explain an unexplained technical phenomenon and thereby generate new technical knowledge.
Deep learning as an instrument in explanatory research into a protein mechanism can fit within technical scientific research. A data model that uses historical data to predict an optimal cleaning strategy usually does not qualify, because the research is not explanatory.
A predictive model that merely extracts correlations from data is therefore not automatically technical scientific research.
Use exactly the structure of the current RVO form for research projects:
Have your research project assessed in advance, so that the application answers these parts convincingly and concretely.
RVO requires the research process and results to be recorded transparently. Think of:
See the full requirements at WBSO project records.
In research, costs and expenditures directly attributable to the research can also be relevant in addition to R&D hours, for example specific consumables or research equipment. For actual costs and expenditures, strict rules apply on direct attributability and service to the R&D.
Explanatory research into a technical phenomenon for which existing knowledge offers no adequate explanation, carried out systematically and according to a plan, aimed at new technical knowledge.
No. It can yield theoretical or practical new technical knowledge; academic fundamentality is not a requirement.
Yes. A practical purpose does not preclude technical scientific research; decisive is that the research itself is explanatory.
No. Merely establishing effects or seeking the best setting is usually insufficient without an explanatory research question.
Not automatically. Predicting or searching for correlations is something other than explaining a technical phenomenon.
A hypothesis can be part of the research design, but RVO assesses more broadly whether the research is systematic, planned and explanatory.
Technical scientific research seeks the why of a phenomenon; development seeks a technically new solution to a bottleneck.
Have it assessed without obligation whether your research question is sufficiently explanatory for technical scientific research.
SOURCES AND SUBSTANTIVE REVIEW
Reviewed by Peter Klaren, WBSO specialist since 2004. Last substantively updated: 21 September 2026.